The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for interaction with antibodies or with other proteins, such as the macromolecular substrates Factors Va or VIIIa. APC regulates blood coagulation by proteolytic inactivation of the blood coagulation cofactors Va and VIIIa.

Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.

3-Feruloyl-4-caffeoylquinic acid is a chlorogenic acid isomer. Chlorogenic acids are relevant coffee quality markers, taste, and aroma precursors as well as important bioactive compounds.